The intestinal bacteria are related to the severity of the disease, the immune response; high cost of mental health seen in ICU by Reuters

© Reuters. An illustration, created at the Centers for Disease Control and Prevention (CDC), shows the 2019 novel coronavirus

By Nancy Lapid (Reuters) – The following is a summary of some of the most recent scientific studies on the new coronavirus and efforts to find treatments and vaccines for COVID-19, the disease caused by the virus. Gut Bacteria Linked to COVID-19 Severity and Immune Response Microscopic organisms living in our intestines can influence the severity of COVID-19 and the body’s immune response to it, and could explain persistent symptoms, the researchers reported Monday in Gut magazine. They found that the gut microorganisms in the COVID-19 patients were very different from those in the uninfected individuals. “COVID patients lack certain good bacteria that are known to regulate our immune systems,” said Dr. Siew Ng of the Chinese University of Hong Kong. The presence of an abnormal variety of gut bacteria, or “dysbiosis,” persists after the virus clears and could play a role in the long-lasting symptoms that affect some patients, he said. His team has developed an oral formula of live bacteria known as probiotics and a special capsule to protect the organisms until they reach the intestine. “Compared to patients receiving standard care, our pilot clinical study showed that more COVID patients who received our microbiological immunity formulation achieved complete resolution of symptoms,” Ng said, adding that those who received it had markers of Significantly reduced inflammation in the blood, a favorable bacteria increase in their feces and they developed neutralizing antibodies against the virus. (https: // Pandemic affects the mental health of ICU workers Almost half of staff working in intensive care units (ICU) in England have severe anxiety, depression or post-traumatic stress disorder, and some feel that would be better off dead, researchers reported Wednesday in Occupational Medicine. The study was conducted in June and July, before Britain began to experience its latest spike in hospitalizations. Among more than 700 healthcare workers in nine ICUs, the 45% met the threshold of probable clinical importance for at least one of four serious mental health disorders: severe depression (6%), post-traumatic stress disorder (40%), severe anxiety (11%), or drinking problems (7 %). More than one in eight reported frequent thoughts of self-harm or suicide in the Poor mental health among ICU staff caring for seriously ill and dying patients with COVID-19 not only gives It affects your quality of life, but it also affects your ability to work effectively, the researchers said. n urgent need for mental health services to be readily accessible to all health workers. (https: // Cooling jackets help COVID-19 nurses to tolerate PPE Nurses in COVID-19 wards who wear cooling vests under their personal protective equipment ( EPP) feel less burdened by heat during their shifts, a small study suggests. Seventeen nurses wore a lightweight cooling vest under their PPE on one day, and PPE only on another day. On both days, the participants ingested an electronic capsule that provides a continuous reading of core body temperature. The vests caused a slight improvement in body temperature, but a much larger improvement in the feeling of being too hot, the researchers reported in the journal Temperature. Only 18% of the nurses reported thermal discomfort and 35% a slightly warm thermal sensation at the end of the day in the vest. That compared to 81% and 94%, respectively, on the day without the vest. “PPE is known to induce heat stress, which increases fatigue and sensory disgust, and is known to impair effective decision-making,” said study co-author Thijs Eijsvogels of Radboud University Medical Center in the Netherlands. Low. CoolOver vests made by Dutch company Inuteq are easy to disinfect and reactivate in a refrigerator, he said, and can extend tolerance time to work and improve recovery for physicians involved in COVID-19 care. (https: // Diabetes adds to COVID-19 risks for Black patients Black patients with type 1 diabetes (T1D) who become infected with the novel coronavirus face a particularly high risk of a diabetes complication that puts life-threatening ketoacidosis, new data shows. Type 1 diabetes usually develops in children or young adults and requires daily insulin to survive. Researchers studied 180 patients from across the United States with type 1 diabetes and COVID-19 , including 31% who were black and 26% Hispanic. Black patients were nearly four times as likely to develop diabetic ketoacidosis (DKA) compared to white patients, the researchers reported in The Journal of Clinical Endocrinology and Metabolism. Hispanics were at slightly higher risk than white patients. Blacks and Hispanics were significantly less likely to use l new diabetes technology such as continuous glucose monitoring and insulin pumps, and had significantly worse blood sugar control compared to white patients. That suggested the higher r in the isk was likely driven by structural and systemic inequality, co-author Dr. Osagie Ebekozien of the nonprofit T1D Exchange in Boston told Reuters. Particularly during the pandemic, healthcare providers should screen Type 1 diabetes patients for socioeconomic factors that increase their risk for CAD, such as food insecurity, insulin affordability and access to diabetes supplies, the researchers said. . Open in an external browser to see a Reuters chart on vaccines and treatments in development.

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